TCU vs. SMU odds, line: 2021 college football picks, Week 4 predictions from proven computer model

The TCU Horned Frogs will take on the SMU Mustangs at noon ET on Saturday at Amon G. Carter Stadium. The two Dallas-area programs are playing each other for the 100th time and TCU holds a 51-41-7 advantage in the series after dominating the rivalry since the turn over the century. However, SMU won the last head-to-head matchup in 2019 as 7.5-point underdogs.

Last season was the first time the two schools haven’t played since 1988 because of the pandemic and both squads are undefeated entering Saturday. The Horned Frogs are favored by 9.5-points in the latest TCU vs. SMU odds from Caesars Sportsbook, and the over-under is set at 65.5. Before entering any SMU vs. TCU picks, you’ll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. It also enters Week 4 of the 2021 season on a 72-58 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on TCU vs. SMU. You can head to SportsLine to see its picks. Here are several college football odds for TCU vs. SMU:

• TCU vs. SMU spread: TCU -9.5
• TCU vs. SMU over-under: 65.5 points

Featured Game | TCU Horned Frogs vs. SMU Mustangs

What you need to know about TCU

The Horned Frogs came out on top in a nail-biter against the California Golden Bears last week, sneaking past 34-32. TCU’s running back Zach Evans was on fire, rushing for one touchdown and 183 yards on 22 carries. That touchdown — a 51-yard rush in the second quarter — was one of the highlights of the game.

Max Duggan is a third-year starter at quarterback for TCU and he’s played well so far this season, completing 62.0 of his passes for 441 yards and four touchdowns while adding 80 yards rushing and two more scores on the ground. Duggan is averaging 8.8 yards per attempt this season and with Evans coming off a monster performance, TCU is going to have opportunities down the field.

What you need to know about SMU

Speaking of close games: SMU narrowly escaped with a win as the squad sidled past the Louisiana Tech Bulldogs 39-37. Quarterback Tanner Mordecai went supernova for SMU as he passed for five touchdowns and 395 yards on 48 attempts in addition to picking up 51 yards on the ground. Mordecai threw a 33-yard touchdown pass to Reggie Roberson Jr. as time expired to win the game.

Mordecai has completed 73.0 percent of his passes for 1,023 yards with 16 touchdowns and just two interceptions on the year. Danny Gray, Grant Calcaterra and Rashee Rice all have double-digit receptions for at least 193 yards and three touchdowns this season and Ulysses Bentley IV has rushed for 250 yards to provide some balance for Sonny Dykes’ offense.

How to make TCU vs. SMU picks

The model has simulated TCU vs. SMU 10,000 times and the results are in. We can tell you that the model is leaning over and it’s also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the pick at SportsLine.

So who wins TCU vs. SMU? And which side of the spread hits almost 60 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.

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