NFL football pool, pick’em, office pool, confidence picks: Choose the Colts in Week 6, 2021

Written by on October 15, 2021

Las Vegas was one of the most popular NFL office pool picks last week, but the Raiders came up short in a loss to Chicago. They are now under an interim head coach after Jon Gruden resigned earlier this week. The Raiders are 3.5-point underdogs in the latest Week 6 NFL odds, providing a tricky decision for your NFL confidence pool picks. Should you fade Las Vegas in your NFL pick’em pools?

The only way to know who you should select in the Raiders game is to look at trusted NFL predictions. Underdogs have been cashing throughout the season, but is this one of the NFL underdogs you should stay away from? Before you make your NFL predictions, you need to see the Week 6 NFL football pool picks from SportsLine’s proven model.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 6 of the 2021 season on an incredible 125-83 run on top-rated NFL picks that dates back to the 2017 season.

More importantly for NFL confidence pool players, the model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports office pool players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated the entire Week 6 NFL schedule 10,000 times and generated its optimal NFL pick’em plays. Go to SportsLine to see them.

Top Week 6 NFL office pool predictions

One of the top Week 6 NFL pick’em predictions from the model: The Colts cruise past the Texans for a comfortable 12-point win. The Colts are in desperation mode after falling to 1-4 with their loss at Baltimore on Monday. They have lost to four quality teams, with their other three setbacks coming against the Seahawks, Rams and Titans. Indianapolis beat Miami in Week 4 and needs to take care of business on Sunday to remain relevant in the NFL playoff picture.

The Texans have lost their last four games after opening the season with a win against Jacksonville. They have dropped three of those games by double-digits, including a 40-0 loss to Buffalo. Houston’s offense has been atrocious, sitting at No. 29 in the NFL at 282.6 yards per game.

SportsLine’s model has Indianapolis winning in 80 percent of simulations. The Colts are also covering the spread almost 60 percent of the time, making them a solid choice for your Week 6 NFL pool picks.

How to make Week 6 NFL office pool picks

The model also made the call on every other Week 6 game and has strong picks for potentially close matchups like Browns vs. Cardinals and Ravens vs. Chargers. It’s also calling for an underdog to win outright. You can only see all of the model’s NFL pool picks here.

So who should you pick in every Week 6 NFL game? And which underdog wins outright? Visit SportsLine now to get optimal NFL office pool picks, all from the advanced computer model that has ranked in the Top 10 on straight-up picks four of the last five years and went an outstanding 125-83 on top-ranked picks since 2017.

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