College football odds, lines, predictions for Championship Week, 2021: Model picks Cincinnati, Oklahoma State

Written by on December 3, 2021

Michigan defeated Ohio State in The Game for the first time since 2011 last week. Now the No. 2 Wolverines are going off as 11-point favorites against No. 13 Iowa in the Big Ten Championship Game, according to Caesars Sportsbook. Other notable matchups on the Championship Week college football schedule includes No. 1 Georgia against No. 3 Alabama (4 p.m. ET, CBS) and No. 4 Cincinnati against No. 21 Houston, among others.

Georgia, favored by 6.5 points in the Championship Week college football odds at Caesars Sportsbook, is fighting to stay undefeated and potentially kick Alabama out of the College Football Playoff field. Cincinnati, favored by 10.5, is battling to become the first Group of Five team to participate in the playoffs. Which of these teams will pull out the win and the cover? Before making any college football picks for Championship Week, be sure to see the latest college football predictions and betting advice from SportsLine’s proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Championship Week 2021 on a 42-28 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest Championship Week college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.

Top college football predictions for Championship Week

One of the top college football picks the model is recommending for Championship Week: No. 4 Cincinnati (-10.5) covers against No. 21 Houston in the AAC Championship Game at 4 p.m. ET on Saturday. Cincinnati is one win away from possibly securing a spot as the first Group of Five team to ever make the College Football Playoff, but Houston has other ideas.

The Cougars ride a hard-charging offense into this one, but they’ll face a Cincinnati defense that has consistently been one of the best in the country all season. The Bearcats cover in 60 percent of simulations from SportsLine’s model, making them a top pick for Championship Week. The point total, which sits at 53, goes over in over 50 percent of simulations as well.

Another one of the college football predictions from the model: No. 5 Oklahoma State (-5.5), fresh off a massive Bedlam win over rival Oklahoma, continues its roll and knocks off the No. 9 Baylor Bears in the Big 12 Championship Game at noon ET on Saturday. The Cowboys have ridden a lights-out defense further than most people thought they’d get, and kept things going in a rivalry week win over Oklahoma to stay alive in the College Football Playoff race. They’ve allowed under 200 total yards in three of their last five games, and held Baylor to 14 points when the teams met in early October.

SportsLine’s simulations project a 10-point OSU win, predicting a score of 27-17. SportsLine’s model has Oklahoma State winning and covering the spread in almost 60 percent of simulations, making the Cowboys a top Championship Week pick. The point total sits at 46.5, and the under hits in almost 60 percent of simulations as well.

How to make Championship Week college football picks 

The model has also made the call on who wins and covers in every other game during the Championship Week college football schedule, and it’s projecting multiple underdogs to win outright. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence? And which underdogs do you need to jump on now? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $3,700 in profit over the past five-plus seasons, and find out.

Championship Week college football odds (via Caesars)

Here are the college football lines for Championship Week:

Friday, Dec. 3

Conference USA: Western Kentucky vs. UTSA (+1.5, 72)

Featured Game | UTSA Roadrunners vs. Western Kentucky Hilltoppers

Pac-12: Oregon vs. Utah (-2.5, 60)

Featured Game | Utah Utes vs. Oregon Ducks

Saturday, Dec. 4

MAC: Kent State vs. Northern Illinois (+3, 72.5)

Featured Game | Northern Illinois Huskies vs. Kent State Golden Flashes

Big 12: Baylor vs. Oklahoma State (-5.5, 46.5)

Featured Game | Oklahoma State Cowboys vs. Baylor Bears

Mountain West: Utah State vs. San Diego State (-6, 50.5)

Featured Game | San Diego State Aztecs vs. Utah State Aggies

Sun Belt: Appalachian State vs. Louisiana (+3, 52.5)

Featured Game | Louisiana Ragin’ Cajuns vs. Appalachian State Mountaineers

SEC: Georgia vs. Alabama (+6.5, 50)

Featured Game | Alabama Crimson Tide vs. Georgia Bulldogs

AAC: Houston vs. Cincinnati (-10.5, 54)

Featured Game | Cincinnati Bearcats vs. Houston Cougars

ACC: Pittsburgh vs. Wake Forest (+3, 72.5)

Featured Game | Wake Forest Demon Deacons vs. Pittsburgh Panthers

Big Ten: Michigan vs. Iowa (+10.5, 43.5)

Featured Game | Iowa Hawkeyes vs. Michigan Wolverines

USC vs. California (-2.5, 57.5)

Featured Game | California Golden Bears vs. USC Trojans

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