Charlotte vs. MTSU odds, line: 2021 college football picks, predictions from model on 72-58 run

The Middle Tennessee Blue Raiders will have a new starting quarterback when they take on the Charlotte 49ers on Friday at Jerry Richardson Stadium in Charlotte, N.C. On Sunday, MTSU quarterback Bailey Hockman, who started the first three games of the season and went 41-of-66 for 463 yards with four touchdowns and two interceptions, informed coach Rick Stockstill that he did not want to play football any longer and wanted to leave the team. He will be replaced by junior Chase Cunningham, who is 19-for-30 for 259 yards, three touchdowns and zero interceptions this season. 

Kickoff is 6:30 p.m. ET. The 49ers are three-point favorites in the latest Charlotte vs. MTSU odds from Caesars Sportsbook, while the over-under for total points scored is 56. Before making any MTSU vs. Charlotte picks make sure you see the college football predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. It also enters Week 4 of the 2021 season on a 72-58 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Charlotte vs. MTSU. You can visit SportsLine now to see the picks. Here are the college football odds and trends for MTSU vs. Charlotte:

• Charlotte vs. Middle Tennessee spread: 49ers -3
• Charlotte vs. Middle Tennessee Under: 56 points
• Charlotte vs. Middle Tennessee money line: 49ers -150, Blue Raiders +130
• CLT: WR Grant DuBose ranks second in Conference USA in yards per reception (27.3).
• MT: The Blue Raiders lead the conference in turnover margin per game (2.0).

Featured Game | Charlotte 49ers vs. Middle Tenn. Blue Raiders

Why Charlotte can cover

Charlotte has a veteran playmaker at quarterback in 5-foot-11 senior Chris Reynolds. A former walk-on from Mocksville, N.C., Reynolds is the program’s all-time passing leader, with 5,627 career passing yards. In the team’s season-opening win against Duke, he threw for 324 yards and three touchdowns and ran for a fourth. He also was 9-of-10 for 161 yards and two touchdowns in the final three minutes, leading the program to its first victory over a Power Five conference team.

In addition, Charlotte has excelled defending the pass this season. The 49ers are allowing just 139.0 passing yards per game, which ranks second in the conference and 10th in the country.

Why MTSU can cover

Middle Tennessee has a playmaker in the defensive backfield in safety Reed Blankenship. A senior from Athens, Ala., Blankenship enters the game with 335 career tackles and needs just 10 more stops to surpass Roosevelt Colvard as the school’s all-time leading tackler. This season he leads the team with 26 tackles and ranks second with three tackles for loss.

In addition, Middle Tennessee faces a Charlotte defense that has struggled to stop the run this season. The 49ers are allowing a whopping 258.0 rushing yards per game; just three teams in the country give up more.

How to make MTSU vs. Charlotte picks

SportsLine’s model is leaning under on the total, projecting the teams to combine for 50 points. The model also says one side of the spread hits in 60 percent of simulations. You can only get the pick at SportsLine. 

So who wins Charlotte vs. MTSU? And which side of the spread hits in 60 percent of simulations? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.  

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