2022 NFL picks, Super Bowl odds, predictions, best bets from top model: This four-way parlay pays 12-1

The last time the Los Angeles Rams advanced to the Super Bowl, Sean McVay was in just his second season as head coach and Zac Taylor was his quarterbacks coach. Three years later, McVay has returned to the NFL title game, but this time, Taylor is on the other sideline as the head coach of the Cincinnati Bengals. Intrigue in the 2022 Super Bowl is high after the Rams made blockbuster moves to acquire players like Odell Beckham Jr. and Von Miller, while upstart Cincinnati made an incredible turnaround from a four-win campaign last season.

Los Angeles is a 4.5-point favorite in the latest 2022 Super Bowl odds from Caesars Sportsbook, while the over-under is 48.5. Before locking in any 2022 Super Bowl picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters the 2022 Super Bowl on an incredible 137-97 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in four confident NFL best bets for Super Bowl LVI. If you successfully parlay its picks, you’d be looking at a massive payout of around 12-1. You can only see the model’s Super Bowl 2022 picks at SportsLine. 

Top 2022 Super Bowl picks

After simulating every snap of Super Bowl LVI 10,000 times, the model is backing Cincinnati running back Joe Mixon to score a touchdown in the game at -111 odds. Mixon ended the regular season as the team leader in touchdowns scored with 16 and was directly involved in 40 percent of Cincinnati’s offensive plays. Mixon finished the regular season with more yards from scrimmage (1,519) than any other Bengals skill player and played in one fewer game than Ja’Marr Chase, who finished with 1,476.

The Rams kept San Francisco’s Elijah Mitchell out of the end zone last Sunday, but they gave up a rushing touchdown to Arizona’s James Conner in the wild card round and two to Tampa Bay’s Leonard Fournette the following week. With tight end C.J. Uzomah’s (knee) status up in the air, the Bengals are likely to do most of their work out of three-wide receiver sets, making it difficult for Los Angeles to stack the box against Mixon. The extra space should create an opportunity for Mixon to find the end zone, and the model projects he scores in 70 percent of simulations.

How to make 2022 Super Bowl parlays

The model locked in Super Bowl LVI picks and says one side of the spread cashes well over 50 percent of the time. You can only see the model’s 2022 Super Bowl best bets and Rams vs. Bengals parlay at SportsLine. 

What are the model’s top picks for Super Bowl LVI? And which other NFL picks should you target for a massive 12-1 payout? Visit SportsLine now to see the Super Bowl best bets from a model on a 137-97 run on its top-rated picks, and find out.