Manchester City vs. Liverpool prediction, odds, line: Expert reveals 2022 FA Cup picks for Saturday, April 16

The English Premier League’s top two teams are at it again on Saturday when Liverpool and Manchester City square off in a FA Cup semifinal. The matchup at London’s Wembley Stadium is the second between the teams in six days. They played to a 2-2 draw in a crucial Premier League match last Sunday, with first-place City maintaining a one-point lead over the Reds in the EPL table. Saturday’s winner will face Chelsea or Crystal Palace, who face off in Sunday’s other semifinal. 

Kickoff in London is set for 10:30 a.m. ET. Caesars Sportsbook lists Man City as the +145 favorite (risk $100 to win $145) on the 90-minute money line in its latest Manchester City vs. Liverpool odds, with Liverpool the +185 underdog. A draw is priced at +245 and the over-under for total goals scored is set at 2.5. Before you lock in your Liverpool vs. Manchester City picks or make any FA Cup predictions, you have to see what proven soccer insider Martin Green has to say. 

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Since then, his European soccer picks have been stunningly accurate. Green has generated almost $35,000 for $100 bettors since the 2017-18 season, and he has his finger on the pulse of the game all over the globe.

Now, Green has broken down Manchester City vs. Liverpool from every angle and just revealed his picks and FA Cup predictions. You can head to SportsLine now to see Green’s picks. Here are the betting lines and trends for Liverpool vs. Manchester City:

• Man City vs. Liverpool spread: City -0.5 (+140)
• Man City vs. Liverpool over-under: 2.5 goals 
• Man City vs. Liverpool money line: City +145, Liverpool +185, Draw +245 
• MC: Manchester City has scored 13 goals in the past five meetings 
• LVP: Liverpool has at least two goals in five of its past six games

Why you should back Manchester City

City has been one of the best defensive teams in the world for a couple of years now, and it won the Premier League title last season. It has conceded 20 goals in its 31 EPL matches and 35 in 49 games overall. It outscored its previous four FA Cup opponents 14-3 and held more than 75 percent possession in two of the matches. The Cityzens don’t have a true striker, but they have five players with at least 10 goals in all competitions this season. 

Kevin De Bruyne injured his ankle Wednesday and is in serious doubt, but players like Phil Foden, Bernardo Silva, Ilkay Gundogan and Gabriel Jesus give City tons of options in attack. Jack Grealish also could play a big role. City holds the ball at a five percent higher rate than any team in the EPL, which gives opponents few opportunities to score (or even shoot). It has allowed 71 shots on target in its 31 EPL matches. Ederson should be in the net for this one, and he has 22 clean sheets in 40 starts and a save percentage of 70.     

Why you should back Liverpool

The Reds should have a major advantage in terms of rest for this one. They played their Champions League match at home, while City had to fly to Madrid. Liverpool manager Jurgen Klopp also took a significant risk in resting several key players Wednesday, and that could pay off Saturday. Meanwhile, City is banged up and is likely to be missing key facilitator De Bruyne. The Reds also have an embarrassment of attacking talent and are very strong on the back end. Its success starts with EPL top scorer Mohamed Salah, who has 20 league goals.

Diogo Jota has shown in this tournament and while Salah was away at the Africa Cup of Nations that he can carry the team. He has two goals in the FA Cup and 15 in the Premier League. Liverpool has conceded 22 league goals and 39 in 51 games overall. A back line featuring Virgil Van Djik and Joel Matip is imposing, and they can get on the end of crosses from set-piece ace Trent Alexander-Arnold.

How to make Liverpool vs. Manchester City picks

Green has broken down Liverpool vs. Manchester City from every angle, and he is leaning over on the goal total. He also provides two other confident best bets and has a full breakdown of the match. He’s only sharing his expert FA Cup picks at SportsLine.

So who wins Manchester City vs. Liverpool in Saturday’s FA Cup semifinal? And where does all the betting value lie? Visit SportsLine now to see the best bets for Liverpool vs. Manchester City, all from the European soccer expert who has generated almost $35,000 for $100 bettors over the past four seasons, and find out.