2022 English Premier League predictions, odds: Liverpool vs. Manchester City picks, April 10 expert best bets

The lead — and quite possibly the title — in the English Premier League will be on the line when first place Manchester City hosts second place Liverpool in a massive showdown on Sunday at Etihad Stadium in Manchester. With eight matches remaining in the season, City leads the table with 73 points. The Reds are one point behind, with 72. They are both far ahead of third place Chelsea. Sunday’s match will go a long way toward determining who raises the Premier League Trophy at the end of the season.

Kickoff is set for 11:30 a.m. ET. Man City is listed as a +103 (risk $100 to win $103) favorite in the latest Manchester City vs. Liverpool odds, while Liverpool is a +255 underdog. A draw is +260, and the over-under for total goals is 2.5. Before making any Liverpool vs. Manchester City picks or English Premier League predictions, you need to see what proven soccer insider Jon Eimer has to say. 

Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, Eimer has covered the English Premier League, Serie A, the FA Cup and much more. The Indiana-based handicapper compiled a winning record of 260-133-1 with over 90 units of profit for his community on various platforms over a recent two-month stretch. He is 13-8 on his English Premier League picks since the start of the calendar year.

Now, Eimer has broken down the Man City vs. Liverpool matchup from every angle and just revealed his coveted Premier League picks and predictions. You can head to SportsLine now to see Eimer’s picks. Here are the betting lines and trends for Liverpool vs. Man City:

• Man City vs. Liverpool spread: City -0.5 (+100) 
• Man City vs. Liverpool over-under: 2.5 goals 
• Man City vs. Liverpool money line: City +103, Liverpool +255, Draw +260 
• MC: Joao Cancelo tops the Premier League in passes into the penalty area (76) 
• LVP: Mohamed Salah leads the league in shots (113) and attempts on target (43)

Why you should back Manchester City

The defending champions have arguably the better midfield. City can start Kevin De Bruyne, Rodrigo and Bernardo Silva. Those three allow the team to dominate possession, which is how manager Pep Guardiola likes to play.

In addition, Phil Foden has had success recently against Liverpool. The 21-year-old forward from Stockport, England, has three goals in his last three matches against the Reds. This season he has seven goals in Premier League play, which ranks fourth on the team.

Why you should back Liverpool

The Reds have the best scorer in the Premier League — and maybe the world — in Mo Salah. The two-time winner of the Premier League’s Golden Boot, Salah leads the League with 20 goals this season. That’s six more than the next best player. In the previous matchup between the teams, a 2-2 draw, Salah scored.

In addition, Liverpool faces a Man City team that will be without Ruben Dias. The 24-year-old center back from Portugal has missed six straight City games with a hamstring injury. His absence is a major blow to City, as he was named both the Premier League Player of the Season and the Champions League Defender of the Season in 2021.

How to make EPL and Man City vs. Liverpool picks

Eimer has analyzed Man City vs. Liverpool and is leaning over (-145) the total. But he has identified two other confident picks for Liverpool vs. Man City, including one that brings back plus-money. He’s sharing these picks only at SportsLine.

Who will win Man City vs. Liverpool? And which best bets should you be all over? Visit SportsLine now to get Jon Eimer’s predictions for the Premier League match, all from the soccer expert who has been on a roll.